ABSTRACT
OBJECTIVE:
The present study assesses the effect of the proportion of
tissue resected during transurethral resections of the
prostate (TUR-P) on
lower urinary tract symptoms (LUTS) and other
parameters in
patients with a benign prostatic obstruction (BPO). MATERIALS AND
METHODS:
Forty-three
patients who underwent TUR-P between 2018 and 2021 were assessed prospectively. The
patients were divided into two groups according to the percentage of
tissue removed (group 1 <30%, group 2 >30% resection). Age,
prostate volume, amount of resected
tissue,
operative time, length of
hospital stay, duration of
catheterization, International
Prostate Symptom Score (IPSS),
quality of life score (QoL), maximum urinary flow rate (Qmax), and
serum prostate-specific antigen (PSA) (ng/dl) at preoperative and postoperative three months were recorded.
RESULTS:
The percentage of
tissue removed was 22.2% vs. 48.4% (p = 0.001), IPSS reduction was 77.7% vs. 83.3% (p = 0.048), QoL improvement was 77.2% vs. 84.8% (p = 0.133), Qmax increase was 171.3% vs. 193.5% (p = 0.032), and
serum PSA decrease was 56.4% vs. 69.2% (p = 0.049) in groups 1 and 2, respectively. In addition, the
operative time was 38.5 vs. 53.6 min (p = 0.001), the length of
hospital stay was 2.0 vs. 2.4 days (p = 0.001), and the duration of
catheterization average was 4.1 vs. 4.9 days (p = 0.002).
CONCLUSION:
Resections of at least 30% of prostatic
tissue can provide a significant improvement in the symptoms and
parameters related to benign prostatic obstruction, while resections of less than 30% of prostatic
tissue can effectively reduce urinary symptoms and improve the
quality of life in older
adult patients with comorbidities
who require shorter operating times.