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Transient Kupffer cell depletion and subsequent replacement by infiltrating monocyte-derived cells does not alter the induction or progression of hepatocellular carcinoma.
Vanderborght, Bart; De Muynck, Kevin; Gijbels, Eva; Lefere, Sander; Scott, Charlotte L; Guilliams, Martin; Beschin, Alain; Vinken, Mathieu; Verhelst, Xavier; Geerts, Anja; Van Vlierberghe, Hans; Devisscher, Lindsey.
Affiliation
  • Vanderborght B; Hepatology Research Unit, Department of Internal Medicine and Pediatrics, Liver Research Center Ghent, Faculty of Medicine and Health Sciences, Ghent University, Ghent, 9000, Belgium.
  • De Muynck K; Gut-Liver Immunopharmacology Unit, Department of Basic and Applied Medical Sciences, Liver Research Center Ghent, Faculty of Medicine and Health Sciences, Ghent University, Ghent, 9000, Belgium.
  • Gijbels E; Hepatology Research Unit, Department of Internal Medicine and Pediatrics, Liver Research Center Ghent, Faculty of Medicine and Health Sciences, Ghent University, Ghent, 9000, Belgium.
  • Lefere S; Gut-Liver Immunopharmacology Unit, Department of Basic and Applied Medical Sciences, Liver Research Center Ghent, Faculty of Medicine and Health Sciences, Ghent University, Ghent, 9000, Belgium.
  • Scott CL; Gut-Liver Immunopharmacology Unit, Department of Basic and Applied Medical Sciences, Liver Research Center Ghent, Faculty of Medicine and Health Sciences, Ghent University, Ghent, 9000, Belgium.
  • Guilliams M; Entity of In Vitro Toxicology and Dermato-Cosmetology, Department of Pharmaceutical and Pharmacological Sciences, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels, 1090, Belgium.
  • Beschin A; Hepatology Research Unit, Department of Internal Medicine and Pediatrics, Liver Research Center Ghent, Faculty of Medicine and Health Sciences, Ghent University, Ghent, 9000, Belgium.
  • Vinken M; Department of Biomedical Molecular Biology, Faculty of Science, Ghent University, Ghent, 9000, Belgium.
  • Verhelst X; Laboratory of Myeloid Cell Biology in Tissue Damage and Inflammation, VIB-UGent Center for Inflammation Research, Ghent, 9000, Belgium.
  • Geerts A; Department of Biomedical Molecular Biology, Faculty of Science, Ghent University, Ghent, 9000, Belgium.
  • Van Vlierberghe H; Laboratory of Myeloid Cell Biology in Tissue Homeostasis and Regeneration, VIB-UGent Center for Inflammation Research, Ghent, 9000, Belgium.
  • Devisscher L; Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, 1090, Belgium.
Int J Cancer ; 152(12): 2615-2628, 2023 06 15.
Article in En | MEDLINE | ID: mdl-36912275
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Full text: 1 Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Carcinogenesis / Tumor-Associated Macrophages / Kupffer Cells / Liver Neoplasms / Liver Neoplasms, Experimental Limits: Animals Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Carcinoma, Hepatocellular / Carcinogenesis / Tumor-Associated Macrophages / Kupffer Cells / Liver Neoplasms / Liver Neoplasms, Experimental Limits: Animals Language: En Year: 2023 Type: Article