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Quantitative determination of lurbinectedin, its unbound fraction and its metabolites in human plasma utilizing ultra-performance LC-MS/MS.
King, Nicholas; Garcia-Martinez, Soledad; Alcaraz, Eider; Grisalena, Alba; Lubomirov, Rubin; Altares, Raquel; Fernandez-Teruel, Carlos; Francesch, Andrés M; Avilés, Pablo M; Fudio, Salvador.
Affiliation
  • King N; Dynakin S.L. Bioanalytical Laboratory, Derio, Spain.
  • Garcia-Martinez S; Dynakin S.L. Bioanalytical Laboratory, Derio, Spain.
  • Alcaraz E; Dynakin S.L. Bioanalytical Laboratory, Derio, Spain.
  • Grisalena A; Dynakin S.L. Bioanalytical Laboratory, Derio, Spain.
  • Lubomirov R; PharmaMar S.A., Clinical Development, Colmenar Viejo (Madrid), Spain.
  • Altares R; PharmaMar S.A., Clinical Development, Colmenar Viejo (Madrid), Spain.
  • Fernandez-Teruel C; PharmaMar S.A., Clinical Development, Colmenar Viejo (Madrid), Spain.
  • Francesch AM; PharmaMar S.A., Research and Development, Colmenar Viejo (Madrid), Spain.
  • Avilés PM; PharmaMar S.A., Research and Development, Colmenar Viejo (Madrid), Spain.
  • Fudio S; PharmaMar S.A., Clinical Development, Colmenar Viejo (Madrid), Spain.
PLoS One ; 18(3): e0283783, 2023.
Article in En | MEDLINE | ID: mdl-36996147
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Full text: 1 Database: MEDLINE Main subject: Carbolines / Tandem Mass Spectrometry Type of study: Guideline Limits: Humans Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Carbolines / Tandem Mass Spectrometry Type of study: Guideline Limits: Humans Language: En Year: 2023 Type: Article