A conformational equilibrium in the nitrogenase MoFe protein with an &#945;-V70I amino acid substitution illuminates the mechanism of H<sub>2</sub> formation.

Lukoyanov, Dmitriy A; Yang, Zhi-Yong; Shisler, Krista; Peters, John W; Raugei, Simone; Dean, Dennis R; Seefeldt, Lance C; Hoffman, Brian M

A conformational equilibrium in the nitrogenase MoFe protein with an α-V70I amino acid substitution illuminates the mechanism of H₂ formation.

Lukoyanov, Dmitriy A; Yang, Zhi-Yong; Shisler, Krista; Peters, John W; Raugei, Simone; Dean, Dennis R; Seefeldt, Lance C; Hoffman, Brian M.

Affiliation

Lukoyanov DA; Department of Chemistry and Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, USA.
Yang ZY; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322, USA.
Shisler K; Institute of Biological Sciences, Washington State University, Pullman, Washington, 99164, USA.
Peters JW; Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, 73019, USA.
Raugei S; Physical and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington, 99352, USA.
Dean DR; Biochemistry Department, Virginia Tech, Blacksburg, Virginia, 24061, USA.
Seefeldt LC; Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322, USA.
Hoffman BM; Department of Chemistry and Molecular Biosciences, Northwestern University, Evanston, Illinois 60208, USA.

Faraday Discuss ; 243(0): 231-252, 2023 07 19.

Article in En | MEDLINE | ID: mdl-37021412

Subject(s)

Molybdoferredoxin; Nitrogenase; Nitrogenase/chemistry; Nitrogenase/metabolism; Molybdoferredoxin/chemistry; Molybdoferredoxin/metabolism; Amino Acid Substitution; Oxidation-Reduction; Molecular Conformation; Amino Acids; Protons

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