SARS-CoV-2 serological assay and viral testing: a report of professional football setting.
Postgrad Med J
; 98(1161): 529-532, 2022 Jul 01.
Article
in En
| MEDLINE
| ID: mdl-37066496
ABSTRACT
PURPOSE OF THE STUDY PCR is the current standard test for the diagnosis of SARS-CoV-2 infection. However, due to its limitations, serological testing is considered an alternative method for detecting SARS-CoV-2 exposure. In this study, we measured the level of SARS-CoV-2 IgM and IgG antibodies of male professional football players and compared the results with the standard PCR test to investigate the association between the two tests. STUDY DESIGN:
Participants were male professional football players and team officials. Nasopharyngeal swabs and peripheral blood samples were collected for the PCR and serological tests, respectively. Also, previous records of COVID-19 testing and symptoms were gathered. Those with previous positive PCR tests who tested negative for the second time were considered to be recovered patients.RESULTS:
Of the 1243 subjects, 222 (17.9%) were seropositive, while 29 (2.3%) tested positive for the SARS-CoV-2 PCR test. Sixty percent of symptomatic cases with a negative PCR were found to be seropositive. The mean level of IgM was significantly higher in PCR-positive and symptomatic subjects, whereas the recovered cases showed significantly higher levels of IgG.CONCLUSION:
Our study revealed an inconsistency of results between the two tests; therefore, although application of serological assays alone seems insufficient in diagnosing COVID-19 disease, the findings are beneficial in the comprehension and the management of the disease.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Football
/
COVID-19
Type of study:
Diagnostic_studies
Limits:
Female
/
Humans
/
Male
Language:
En
Year:
2022
Type:
Article