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Autophagy Inhibition as a Potential Therapeutic Strategy for Breast Cancer with Mitochondrial Translation Defect Caused by CBFB-Deficiency.
Malik, Navdeep; Yan, Hualong; Kim, Young-Im; Ayaz, Gamze; Wang, Shasha; Mondal, Payel; Luo, Ji; Huang, Jing.
Affiliation
  • Malik N; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Yan H; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Kim YI; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Ayaz G; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Wang S; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Mondal P; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Luo J; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Huang J; Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Autophagy ; 19(11): 3026-3028, 2023 11.
Article in En | MEDLINE | ID: mdl-37115099
ABSTRACT
ABBREVIATIONS AMPK, AMP-activated protein kinase; BioID, biotinylation identification; CBFB, core-binding factor subunit beta; HCQ, hydroxychloroquine; HNRNPK, heterogeneous nuclear ribonucleoprotein K; PDX, patient-derived xenograft; PIK3CA, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; TUFM, Tu translation elongation factor, mitochondrial; ETC, electron transport chain.
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Breast Neoplasms Type of study: Prognostic_studies Limits: Female / Humans Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Autophagy / Breast Neoplasms Type of study: Prognostic_studies Limits: Female / Humans Language: En Year: 2023 Type: Article