Ketonization of Ginsenoside C-K by Novel Recombinant 3-ß-Hydroxysteroid Dehydrogenases and Effect on Human Fibroblast Cells.

Jin, Yan; Wang, Dandan; Im, Wan-Taek; Siddiqi, Muhammad Zubair; Yang, Deok-Chun

Jin, Yan; Wang, Dandan; Im, Wan-Taek; Siddiqi, Muhammad Zubair; Yang, Deok-Chun.

Affiliation

Jin Y; School of Life Science, Nantong University, Nantong 226019, China.
Wang D; College of Life Sciences, Yantai University, Yantai 264005, China.
Im WT; Department of Biotechnology, Hankyong National University, 327 Jungang-ro, Anseong-si 17579, Gyeonggi-do, Republic of Korea.
Siddiqi MZ; Department of Oriental Medicinal Material & Processing, College of Life Science, Kyung Hee University, Seocheon-dong, Giheung-gu, Yongin-si 17104, Gyeonggi-do, Republic of Korea.
Yang DC; Department of Biotechnology, Hankyong National University, 327 Jungang-ro, Anseong-si 17579, Gyeonggi-do, Republic of Korea.

Molecules ; 28(9)2023 Apr 28.

Article in En | MEDLINE | ID: mdl-37175202

Subject(s)

Ginsenosides; Humans; Ginsenosides/chemistry; Biotransformation; Glycoside Hydrolases/metabolism; Fibroblasts/metabolism; 3-Hydroxysteroid Dehydrogenases/metabolism; beta-Glucosidase/metabolism

Key words

3-oxo-C-K; 3-ß-hydroxysteroid dehydrogenase; Lactobacillus brevis DCY65-1; ginsenoside C-K; ketonization

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