Serum pro-surfactant protein B is correlated with clinical properties in osteosarcoma patients.
Biochem Cell Biol
; 101(5): 456-463, 2023 10 01.
Article
in En
| MEDLINE
| ID: mdl-37192548
ABSTRACT
It is critical to find efficient non-invasive prognostic factor for osteosarcoma. In this study, we demonstrated that serum protein of pro-surfactant protein B (pro-SFTPB) may be a potential diagnostic indicator in osteosarcoma. We found that serum pro-SFTPB was highly expressed in osteosarcoma patients and presented good diagnostic value to discern osteosarcoma patients from non-osteosarcoma control subjects. Serum pro-SFTPB was also significantly correlated with advanced clinical stage, distant metastasis, and shorter overall survival. In addition, serum pro-SFTPB was demonstrated to be an independent prognostic factor for osteosarcoma. Overall, our study demonstrated that serum pro-SFTPB may be a useful diagnostic factor for osteosarcoma.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Bone Neoplasms
/
Osteosarcoma
Type of study:
Prognostic_studies
Limits:
Humans
Language:
En
Year:
2023
Type:
Article