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Granulocyte transfusion during cord blood transplant for relapsed, refractory AML is associated with massive CD8+ T-cell expansion, significant cytokine release syndrome and induction of disease remission.
Borrill, Roisin; Poulton, Kay; Kusyk, Laura; Routledge, Amy; Bonney, Denise; Hanasoge-Nataraj, Ramya; Powys, Madeleine; Mustafa, Omima; Campbell, Helen; Senthil, Srividhya; Dillon, Richard; Jovanovic, Jelena; Morton, Suzy; James, Beki; Rao, Kanchan; Stanworth, Simon; Konkel, Joanne; Wynn, Robert.
Affiliation
  • Borrill R; Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Poulton K; Lydia Becker Institute of Immunology and Inflammation, Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
  • Kusyk L; Transplantation Laboratory, Manchester University NHS Foundation Trust, Manchester, UK.
  • Routledge A; Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
  • Bonney D; Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Hanasoge-Nataraj R; Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Powys M; Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Mustafa O; Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Campbell H; Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Senthil S; Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Dillon R; Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Jovanovic J; Blood and Marrow Transplant Unit, Royal Manchester Children's Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Morton S; Department of Medical and Molecular Genetics, Kings College London, London, UK.
  • James B; Department of Medical and Molecular Genetics, Kings College London, London, UK.
  • Rao K; NHS Blood and Transplant, Birmingham, UK.
  • Stanworth S; Leeds Children's Hospital, Leeds General Infirmary, Leeds, UK.
  • Konkel J; Department of Blood and Marrow Transplantation, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
  • Wynn R; NHS Blood and Transplant, Oxford, UK.
Br J Haematol ; 202(3): 589-598, 2023 08.
Article in En | MEDLINE | ID: mdl-37211883
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Full text: 1 Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Cord Blood Stem Cell Transplantation Type of study: Risk_factors_studies Limits: Child / Humans Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Cord Blood Stem Cell Transplantation Type of study: Risk_factors_studies Limits: Child / Humans Language: En Year: 2023 Type: Article