[A Case of Advanced Esophageal Cancer with Esophago-Bronchial Fistula Closed by Pembrolizumab plus Chemotherapy Therapy].
Gan To Kagaku Ryoho
; 50(5): 627-629, 2023 May.
Article
in Ja
| MEDLINE
| ID: mdl-37218326
ABSTRACT
We report a case of unresectable advanced esophageal cancer with an esophageal fistula that was treated with pembrolizumab plus CDDP plus 5-FU therapy and the fistula was closed. A 73-year-old male was diagnosed with cervical-upper thoracic esophageal cancer and esophago-bronchial fistula on CT and esophagogastroduodenoscopy. He underwent chemotherapy containing pembrolizumab. The fistula was closed after 4 cycles and oral intake became possible. Six months have passed since the first visit and chemotherapy is ongoing. The prognosis of esophago-bronchial fistula is extremely poor, and there is no established treatment, including fistula closure. Chemotherapy containing immune checkpoint inhibitors could considered to be expected not only for local control but also for long-term survival.
Search on Google
Database:
MEDLINE
Main subject:
Esophageal Neoplasms
/
Bronchial Fistula
/
Esophageal Fistula
Type of study:
Etiology_studies
/
Prognostic_studies
Limits:
Aged
/
Humans
/
Male
Language:
Ja
Year:
2023
Type:
Article