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Ability of a polygenic risk score to refine colorectal cancer risk in Lynch syndrome.
Dueñas, Nuria; Klinkhammer, Hannah; Bonifaci, Nuria; Spier, Isabel; Mayr, Andreas; Hassanin, Emadeldin; Diez-Villanueva, Anna; Moreno, Victor; Pineda, Marta; Maj, Carlo; Capellà, Gabriel; Aretz, Stefan; Brunet, Joan.
Affiliation
  • Dueñas N; Hereditary Cancer Program, Catalan Institute of Oncology - ICO, L'Hospitalet de Llobregat, Spain.
  • Klinkhammer H; Hereditary Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.
  • Bonifaci N; Biomedical Research Centre Network for Oncology (CIBERONC), Instituto Salud Carlos III, Madrid, Spain.
  • Spier I; European Reference Network on Genetic Tumour Risk Syndromes (ERN GENTURIS), Nijmegen, Netherlands.
  • Mayr A; Institute for Medical Biometry, Informatics and Epidemiology, Medical Faculty, University of Bonn, Bonn, Germany.
  • Hassanin E; Institute for Genomic Statistics and Bioinformatics, Medical Faculty, University of Bonn, Bonn, Germany.
  • Diez-Villanueva A; Hereditary Cancer Group, Molecular Mechanisms and Experimental Therapy in Oncology Program, Institut d'Investigació Biomèdica de Bellvitge - IDIBELL, L'Hospitalet de Llobregat, Spain.
  • Moreno V; Biomedical Research Centre Network for Oncology (CIBERONC), Instituto Salud Carlos III, Madrid, Spain.
  • Pineda M; European Reference Network on Genetic Tumour Risk Syndromes (ERN GENTURIS), Nijmegen, Netherlands.
  • Maj C; Institute of Human Genetics, Medical Faculty, University of Bonn, Bonn, Germany.
  • Capellà G; National Center for Hereditary Tumor Syndromes, University of Bonn, Bonn, Germany.
  • Aretz S; Institute for Medical Biometry, Informatics and Epidemiology, Medical Faculty, University of Bonn, Bonn, Germany.
  • Brunet J; Institute for Genomic Statistics and Bioinformatics, Medical Faculty, University of Bonn, Bonn, Germany.
J Med Genet ; 60(11): 1044-1051, 2023 Nov.
Article in En | MEDLINE | ID: mdl-37321833
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Full text: 1 Database: MEDLINE Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Language: En Year: 2023 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Language: En Year: 2023 Type: Article