AAV-mediated expression of a new conformational anti-aggregated &#945;-synuclein antibody prolongs survival in a genetic model of &#945;-synucleinopathies.

AAV-mediated expression of a new conformational anti-aggregated α-synuclein antibody prolongs survival in a genetic model of α-synucleinopathies.

Düchs, Matthias; Blazevic, Dragica; Rechtsteiner, Philipp; Kenny, Cynthia; Lamla, Thorsten; Low, Sarah; Savistchenko, Jimmy; Neumann, Manuela; Melki, Ronald; Schönberger, Tanja; Stierstorfer, Birgit; Wyatt, David; Igney, Frederik; Ciossek, Thomas.

Affiliation

Düchs M; Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Blazevic D; Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Rechtsteiner P; Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Kenny C; Boehringer Ingelheim USA, Ridgefield, CT, USA.
Lamla T; Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Low S; Boehringer Ingelheim USA, Ridgefield, CT, USA.
Savistchenko J; Institut Francois Jacob (MIRCen), CEA, CNRS, Fontenay-aux-Roses, France.
Neumann M; Molecular Neuropathology of Neurodegenerative Diseases, German Center for Neurodegenerative Diseases, Tübingen, Germany.
Melki R; Department of Neuropathology, University Hospital of Tübingen, Tübingen, Germany.
Schönberger T; Institut Francois Jacob (MIRCen), CEA, CNRS, Fontenay-aux-Roses, France.
Stierstorfer B; Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Wyatt D; Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Igney F; Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.
Ciossek T; Boehringer Ingelheim Pharma GmbH & Co KG, Biberach an der Riss, Germany.

NPJ Parkinsons Dis ; 9(1): 91, 2023 Jun 15.

Article in En | MEDLINE | ID: mdl-37322068

Full text: 1 Database: MEDLINE Language: En Year: 2023 Type: Article

Full text: 1 Database: MEDLINE Language: En Year: 2023 Type: Article