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Duffy-Null Phenotype-Associated Neutropenia is the Most Common Etiology for Leukopenia/Neutropenia Referrals to a Tertiary Children's Hospital.
Gay, Kelsey; Dulay, Kristopher; Ravindranath, Yaddanapudi; Savasan, Süreyya.
Affiliation
  • Gay K; Children's Hospital of Michigan, Detroit, MI; Penn State Children's Hospital, Hershey, PA.
  • Dulay K; Division of Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI.
  • Ravindranath Y; Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI.
  • Savasan S; Division of Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI; Division of Hematology/Oncology, Pediatric Blood and Marrow Transplant Program, Barbara Ann Karmanos Cancer Center, Children's Hospital of Michigan, Detroit, MI; Department of Pediatrics, Central Michigan University Colle
J Pediatr ; 262: 113608, 2023 11.
Article in En | MEDLINE | ID: mdl-37419240
ABSTRACT
Duffy-null phenotype-associated neutropenia was present in 77.7% of leukopenia/neutropenia referrals to our center in Detroit with a high prevalence in Yemeni (96.6%), African American (91%), and non-Yemeni Middle Eastern (52.9%) patients. Greater availability of Duffy typing in patients with neutropenia but without recurrent/frequent/serious infections may lessen the need for additional consultations and investigations.
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Full text: 1 Database: MEDLINE Main subject: Duffy Blood-Group System / Neutropenia Type of study: Etiology_studies / Risk_factors_studies Limits: Child / Humans Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Duffy Blood-Group System / Neutropenia Type of study: Etiology_studies / Risk_factors_studies Limits: Child / Humans Language: En Year: 2023 Type: Article