Multi-attribute analysis of adeno-associated virus by size exclusion chromatography with fluorescence and triple-wavelength UV detection.

Xie, Yongjing; Butler, Michael

Xie, Yongjing; Butler, Michael.

Affiliation

Xie Y; National Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Blackrock, Co. Dublin, A94 X099, Ireland.
Butler M; National Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Blackrock, Co. Dublin, A94 X099, Ireland; School of Chemical and Bioprocess Engineering, University College Dublin (UCD), Belfield, Dublin 4, D04 V1W8, Ireland. Electronic address: michael.butler@nibrt.ie.

Anal Biochem ; 680: 115311, 2023 11 01.

Article in En | MEDLINE | ID: mdl-37666384

Subject(s)

Capsid Proteins; Dependovirus; Dependovirus/genetics; Chromatography, Gel; Capsid Proteins/genetics; Genetic Therapy; Tryptophan

Key words

Adeno-associated virus; Empty and full capsids; Gene therapy; Multi-attribute analysis; Size exclusion chromatography; Viral vector

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Full text: 1 Database: MEDLINE Main subject: Dependovirus / Capsid Proteins Type of study: Diagnostic_studies / Risk_factors_studies Language: En Year: 2023 Type: Article

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PubMed Links

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Full text: 1 Database: MEDLINE Main subject: Dependovirus / Capsid Proteins Type of study: Diagnostic_studies / Risk_factors_studies Language: En Year: 2023 Type: Article