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Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.
He, Yachao; Kaya, Ibrahim; Shariatgorji, Reza; Lundkvist, Johan; Wahlberg, Lars U; Nilsson, Anna; Mamula, Dejan; Kehr, Jan; Zareba-Paslawska, Justyna; Biverstål, Henrik; Chergui, Karima; Zhang, Xiaoqun; Andren, Per E; Svenningsson, Per.
Affiliation
  • He Y; Translational Neuropharmacology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden. yachao.he@ki.se.
  • Kaya I; Department of Pharmaceutical Biosciences, Medical Mass Spectrometry Imaging, Uppsala University, Uppsala, Sweden.
  • Shariatgorji R; Department of Pharmaceutical Biosciences, Medical Mass Spectrometry Imaging, Uppsala University, Uppsala, Sweden.
  • Lundkvist J; Science for Life Laboratory, Spatial Mass Spectrometry, Uppsala University, Uppsala, Sweden.
  • Wahlberg LU; Division of Neurogeriatrics, Department of Neurobiology, Care Science and Society, Karolinska Institutet, Stockholm, Sweden.
  • Nilsson A; Sinfonia Biotherapeutics AB, Huddinge, Sweden.
  • Mamula D; Division of Neurogeriatrics, Department of Neurobiology, Care Science and Society, Karolinska Institutet, Stockholm, Sweden.
  • Kehr J; Department of Pharmaceutical Biosciences, Medical Mass Spectrometry Imaging, Uppsala University, Uppsala, Sweden.
  • Zareba-Paslawska J; Science for Life Laboratory, Spatial Mass Spectrometry, Uppsala University, Uppsala, Sweden.
  • Biverstål H; Translational Neuropharmacology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Chergui K; Section of Pharmacological Neurochemistry, Department of Physiology and Pharmacology, Karolinska Institute, Solna, Sweden.
  • Zhang X; Translational Neuropharmacology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
  • Andren PE; Sinfonia Biotherapeutics AB, Huddinge, Sweden.
  • Svenningsson P; Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden.
Nat Commun ; 14(1): 5804, 2023 09 19.
Article in En | MEDLINE | ID: mdl-37726325
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Full text: 1 Database: MEDLINE Main subject: Parkinson Disease / Alpha-Synuclein Limits: Animals Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Parkinson Disease / Alpha-Synuclein Limits: Animals Language: En Year: 2023 Type: Article