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Aging-disturbed FUS phase transition impairs hematopoietic stem cells by altering chromatin structure.
Tang, Baixue; Wang, Xinming; He, Hanqing; Chen, Ruiqing; Qiao, Guofeng; Yang, Yang; Xu, Zihan; Wang, Longteng; Dong, Qiongye; Yu, Jia; Zhang, Michael Q; Shi, Minglei; Wang, Jianwei.
Affiliation
  • Tang B; Department of Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
  • Wang X; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
  • He H; Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.
  • Chen R; Department of Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
  • Qiao G; Department of Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
  • Yang Y; Department of Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
  • Xu Z; Department of Biology, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
  • Wang L; School of Life Sciences, Joint Graduate Program of Peking-Tsinghua-National Institute of Biological Sciences, Peking University, Beijing, China.
  • Dong Q; School of Life Sciences, Joint Graduate Program of Peking-Tsinghua-National Institute of Biological Sciences, Peking University, Beijing, China.
  • Yu J; Institute of Precision of Medicine, Peking University Shenzhen Hospital, Shenzhen, China.
  • Zhang MQ; State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
  • Shi M; Ministry of Education Key Laboratory of Bioinformatics, Bioinformatics Division and Center for Synthetic and Systems Biology, Beijing National Research Center for Information Science and Technology, School of Medicine, Tsinghua University, Beijing, China.
  • Wang J; Department of Biological Sciences, Center for Systems Biology, The University of Texas, Richardson, TX.
Blood ; 143(2): 124-138, 2024 Jan 11.
Article in En | MEDLINE | ID: mdl-37748139
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Full text: 1 Database: MEDLINE Main subject: Aging / Hematopoietic Stem Cells Limits: Animals Language: En Year: 2024 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Aging / Hematopoietic Stem Cells Limits: Animals Language: En Year: 2024 Type: Article