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Intrinsic targeting of host RNA by Cas13 constrains its utility.
Li, Zexu; Li, Zihan; Cheng, Xiaolong; Wang, Shengnan; Wang, Xiaofeng; Ma, Shixin; Lu, Zhiyan; Zhang, Han; Zhao, Wenchang; Chen, Zhisong; Yao, Yingjia; Zhang, Cheng; Chao, Lumen; Li, Wei; Fei, Teng.
Affiliation
  • Li Z; Key Laboratory of Bioresource Research and Development of Liaoning Province, College of Life and Health Sciences, Northeastern University, Shenyang, China.
  • Li Z; National Frontiers Science Center for Industrial Intelligence and Systems Optimization, Northeastern University, Shenyang, China.
  • Cheng X; Key Laboratory of Data Analytics and Optimization for Smart Industry (Northeastern University), Ministry of Education, Shenyang, China.
  • Wang S; Key Laboratory of Bioresource Research and Development of Liaoning Province, College of Life and Health Sciences, Northeastern University, Shenyang, China.
  • Wang X; National Frontiers Science Center for Industrial Intelligence and Systems Optimization, Northeastern University, Shenyang, China.
  • Ma S; Key Laboratory of Data Analytics and Optimization for Smart Industry (Northeastern University), Ministry of Education, Shenyang, China.
  • Lu Z; Center for Genetic Medicine Research, Children's National Hospital, Washington, DC, USA.
  • Zhang H; Department of Genomics and Precision Medicine, George Washington University, Washington, DC, USA.
  • Zhao W; Key Laboratory of Bioresource Research and Development of Liaoning Province, College of Life and Health Sciences, Northeastern University, Shenyang, China.
  • Chen Z; National Frontiers Science Center for Industrial Intelligence and Systems Optimization, Northeastern University, Shenyang, China.
  • Yao Y; Key Laboratory of Data Analytics and Optimization for Smart Industry (Northeastern University), Ministry of Education, Shenyang, China.
  • Zhang C; Key Laboratory of Bioresource Research and Development of Liaoning Province, College of Life and Health Sciences, Northeastern University, Shenyang, China.
  • Chao L; National Frontiers Science Center for Industrial Intelligence and Systems Optimization, Northeastern University, Shenyang, China.
  • Li W; Key Laboratory of Data Analytics and Optimization for Smart Industry (Northeastern University), Ministry of Education, Shenyang, China.
  • Fei T; Key Laboratory of Bioresource Research and Development of Liaoning Province, College of Life and Health Sciences, Northeastern University, Shenyang, China.
Nat Biomed Eng ; 8(2): 177-192, 2024 Feb.
Article in En | MEDLINE | ID: mdl-37872368
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Full text: 1 Database: MEDLINE Main subject: RNA / CRISPR-Cas Systems Limits: Animals Language: En Year: 2024 Type: Article
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Full text: 1 Database: MEDLINE Main subject: RNA / CRISPR-Cas Systems Limits: Animals Language: En Year: 2024 Type: Article