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Human isogenic cells of the neurovascular unit exert transcriptomic cell type-specific effects on a blood-brain barrier in vitro model of late-onset Alzheimer disease.
Haferkamp, Undine; Hartmann, Carla; Abid, Chaudhry Luqman; Brachner, Andreas; Höchner, Alevtina; Gerhartl, Anna; Harwardt, Bernadette; Leckzik, Selin; Leu, Jennifer; Metzger, Marco; Nastainczyk-Wulf, Marina; Neuhaus, Winfried; Oerter, Sabrina; Pless, Ole; Rujescu, Dan; Jung, Matthias; Appelt-Menzel, Antje.
Affiliation
  • Haferkamp U; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, 22525, Hamburg, Germany.
  • Hartmann C; Institute for Physiological Chemistry, Medical Faculty of the Martin, Luther University Halle-Wittenberg, Hollystrasse 1, 06114, Halle (Saale), Germany.
  • Abid CL; Institute for Physiological Chemistry, Medical Faculty of the Martin, Luther University Halle-Wittenberg, Hollystrasse 1, 06114, Halle (Saale), Germany.
  • Brachner A; Center Health and Bioresources, Competence Unit Molecular Diagnostics, AIT Austrian Institute of Technology GmbH, Vienna, 1210, Austria.
  • Höchner A; Fraunhofer Institute for Silicate Research ISC, Translational Center Regenerative Therapies (TLC-RT), 97070, Würzburg, Germany.
  • Gerhartl A; Center Health and Bioresources, Competence Unit Molecular Diagnostics, AIT Austrian Institute of Technology GmbH, Vienna, 1210, Austria.
  • Harwardt B; Institute for Physiological Chemistry, Medical Faculty of the Martin, Luther University Halle-Wittenberg, Hollystrasse 1, 06114, Halle (Saale), Germany.
  • Leckzik S; Institute for Physiological Chemistry, Medical Faculty of the Martin, Luther University Halle-Wittenberg, Hollystrasse 1, 06114, Halle (Saale), Germany.
  • Leu J; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, 22525, Hamburg, Germany.
  • Metzger M; Fraunhofer Institute for Silicate Research ISC, Translational Center Regenerative Therapies (TLC-RT), 97070, Würzburg, Germany.
  • Nastainczyk-Wulf M; Chair Tissue Engineering and Regenerative Medicine (TERM), University Hospital Würzburg, 97070, Würzburg, Germany.
  • Neuhaus W; Institute of Legal Medicine, University Hospital, 06112, Halle (Saale), Germany.
  • Oerter S; Center Health and Bioresources, Competence Unit Molecular Diagnostics, AIT Austrian Institute of Technology GmbH, Vienna, 1210, Austria.
  • Pless O; Department of Medicine, Faculty of Medicine and Dentistry, Danube Private University, Krems, 3500, Austria.
  • Rujescu D; Fraunhofer Institute for Silicate Research ISC, Translational Center Regenerative Therapies (TLC-RT), 97070, Würzburg, Germany.
  • Jung M; Chair Tissue Engineering and Regenerative Medicine (TERM), University Hospital Würzburg, 97070, Würzburg, Germany.
  • Appelt-Menzel A; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Discovery Research ScreeningPort, 22525, Hamburg, Germany.
Fluids Barriers CNS ; 20(1): 78, 2023 Oct 31.
Article in En | MEDLINE | ID: mdl-37907966

Full text: 1 Database: MEDLINE Main subject: Induced Pluripotent Stem Cells / Alzheimer Disease Limits: Humans Language: En Year: 2023 Type: Article

Full text: 1 Database: MEDLINE Main subject: Induced Pluripotent Stem Cells / Alzheimer Disease Limits: Humans Language: En Year: 2023 Type: Article