Structural Analysis and Characterization of an Antiproliferative Lectin from <i>Canavalia villosa</i> Seeds.

Lossio, Claudia F; Osterne, Vinicius J S; Pinto-Junior, Vanir R; Chen, Simin; Oliveira, Messias V; Verduijn, Joost; Verbeke, Isabel; Serna, Sonia; Reichardt, Niels C; Skirtach, Andre; Cavada, Benildo S; Van Damme, Els J M; Nascimento, Kyria S

Structural Analysis and Characterization of an Antiproliferative Lectin from Canavalia villosa Seeds.

Lossio, Claudia F; Osterne, Vinicius J S; Pinto-Junior, Vanir R; Chen, Simin; Oliveira, Messias V; Verduijn, Joost; Verbeke, Isabel; Serna, Sonia; Reichardt, Niels C; Skirtach, Andre; Cavada, Benildo S; Van Damme, Els J M; Nascimento, Kyria S.

Affiliation

Lossio CF; Laboratory of Biologically Active Molecules, Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza 60440-970, Brazil.
Osterne VJS; Laboratory of Biologically Active Molecules, Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza 60440-970, Brazil.
Pinto-Junior VR; Laboratory of Biochemistry and Glycobiology, Department of Biotechnology, Ghent University, 9000 Ghent, Belgium.
Chen S; Laboratory of Biologically Active Molecules, Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza 60440-970, Brazil.
Oliveira MV; Department of Physics, Federal University of Ceara, Fortaleza 60440-970, Brazil.
Verduijn J; Laboratory of Biochemistry and Glycobiology, Department of Biotechnology, Ghent University, 9000 Ghent, Belgium.
Verbeke I; Laboratory of Biologically Active Molecules, Department of Biochemistry and Molecular Biology, Federal University of Ceara, Fortaleza 60440-970, Brazil.
Serna S; Nano-Biotechnology Group, Department of Biotechnology, Ghent University, 9000 Ghent, Belgium.
Reichardt NC; Laboratory of Biochemistry and Glycobiology, Department of Biotechnology, Ghent University, 9000 Ghent, Belgium.
Skirtach A; Glycotechnology Lab, Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), Paseo de Miramon 194, 20014 Donostia-San Sebastián, Spain.
Cavada BS; Glycotechnology Lab, Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), Paseo de Miramon 194, 20014 Donostia-San Sebastián, Spain.
Van Damme EJM; Centro de Investigación Biomédica en Red (CIBER-BBN), Paseo de Miramon 194, 20014 Donostia-San Sebastián, Spain.
Nascimento KS; Nano-Biotechnology Group, Department of Biotechnology, Ghent University, 9000 Ghent, Belgium.

Int J Mol Sci ; 24(21)2023 Nov 04.

Article in En | MEDLINE | ID: mdl-37958949

Subject(s)

Canavalia; Lectins; Lectins/pharmacology; Lectins/analysis; Canavalia/metabolism; Molecular Docking Simulation; Plant Lectins/metabolism; Seeds/metabolism; Carbohydrates/analysis; Polysaccharides/analysis

Key words

Canavalia villosa; cancer; glycans; lectin

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