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Resistance gene-guided genome mining reveals the roseopurpurins as inhibitors of cyclin-dependent kinases.
Dunbar, Kyle L; Perlatti, Bruno; Liu, Nicholas; Cornelius, Amber; Mummau, Daniel; Chiang, Yi-Ming; Hon, Lawrence; Nimavat, Monika; Pallas, Jason; Kordes, Sina; Ng, Ho Leung; Harvey, Colin J B.
Affiliation
  • Dunbar KL; Hexagon Bio, Menlo Park, CA 94025.
  • Perlatti B; Hexagon Bio, Menlo Park, CA 94025.
  • Liu N; Hexagon Bio, Menlo Park, CA 94025.
  • Cornelius A; Hexagon Bio, Menlo Park, CA 94025.
  • Mummau D; Hexagon Bio, Menlo Park, CA 94025.
  • Chiang YM; Hexagon Bio, Menlo Park, CA 94025.
  • Hon L; Hexagon Bio, Menlo Park, CA 94025.
  • Nimavat M; Hexagon Bio, Menlo Park, CA 94025.
  • Pallas J; Hexagon Bio, Menlo Park, CA 94025.
  • Kordes S; Proteros Biostructures GmbH, Planegg D-82152, Germany.
  • Ng HL; Hexagon Bio, Menlo Park, CA 94025.
  • Harvey CJB; Hexagon Bio, Menlo Park, CA 94025.
Proc Natl Acad Sci U S A ; 120(48): e2310522120, 2023 Nov 28.
Article in En | MEDLINE | ID: mdl-37983497
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Full text: 1 Database: MEDLINE Main subject: Cyclin-Dependent Kinases / Neoplasms Limits: Humans Language: En Year: 2023 Type: Article
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: 1 Database: MEDLINE Main subject: Cyclin-Dependent Kinases / Neoplasms Limits: Humans Language: En Year: 2023 Type: Article