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Structural principles of peptide-centric chimeric antigen receptor recognition guide therapeutic expansion.
Sun, Yi; Florio, Tyler J; Gupta, Sagar; Young, Michael C; Marshall, Quinlen F; Garfinkle, Samuel E; Papadaki, Georgia F; Truong, Hau V; Mycek, Emily; Li, Peiyao; Farrel, Alvin; Church, Nicole L; Jabar, Shereen; Beasley, Matthew D; Kiefel, Ben R; Yarmarkovich, Mark; Mallik, Leena; Maris, John M; Sgourakis, Nikolaos G.
Affiliation
  • Sun Y; Center for Computational and Genomic Medicine and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Florio TJ; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Gupta S; Center for Computational and Genomic Medicine and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Young MC; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Marshall QF; Center for Computational and Genomic Medicine and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Garfinkle SE; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Papadaki GF; Center for Computational and Genomic Medicine and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Truong HV; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Mycek E; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Li P; Center for Computational and Genomic Medicine and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Farrel A; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Church NL; Center for Computational and Genomic Medicine and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Jabar S; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Beasley MD; Center for Computational and Genomic Medicine and Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Kiefel BR; Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Yarmarkovich M; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Mallik L; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Maris JM; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Sgourakis NG; Myrio Tx, Melbourne, Victoria, Australia.
Sci Immunol ; 8(90): eadj5792, 2023 12.
Article in En | MEDLINE | ID: mdl-38039376
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Full text: 1 Database: MEDLINE Main subject: Receptors, Chimeric Antigen Limits: Humans Language: En Year: 2023 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Receptors, Chimeric Antigen Limits: Humans Language: En Year: 2023 Type: Article