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A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection.
Adams, Lucas J; VanBlargan, Laura A; Liu, Zhuoming; Gilchuk, Pavlo; Zhao, Haiyan; Chen, Rita E; Raju, Saravanan; Chong, Zhenlu; Whitener, Bradley M; Shrihari, Swathi; Jethva, Prashant N; Gross, Michael L; Crowe, James E; Whelan, Sean P J; Diamond, Michael S; Fremont, Daved H.
Affiliation
  • Adams LJ; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • VanBlargan LA; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Liu Z; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Gilchuk P; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Zhao H; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Chen RE; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Raju S; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Chong Z; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Whitener BM; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Shrihari S; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.
  • Jethva PN; Department of Chemistry, Washington University, St. Louis, MO 63130, USA.
  • Gross ML; Department of Chemistry, Washington University, St. Louis, MO 63130, USA.
  • Crowe JE; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Whelan SPJ; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.
  • Diamond MS; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, M
  • Fremont DH; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA; Department of Biochemistry and Molecular Biophysics, Washington University Sch
Cell Rep Med ; 4(12): 101305, 2023 12 19.
Article in En | MEDLINE | ID: mdl-38039973
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Full text: 1 Database: MEDLINE Main subject: Antibodies, Neutralizing / COVID-19 Limits: Animals Language: En Year: 2023 Type: Article
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Antibodies, Neutralizing / COVID-19 Limits: Animals Language: En Year: 2023 Type: Article