Ankle-brachial index associates with arteriovenous fistula stenosis.
J Vasc Access
; : 11297298231226155, 2024 Feb 07.
Article
in En
| MEDLINE
| ID: mdl-38326930
ABSTRACT
BACKGROUND:
Arteriovenous fistula (AVF) stenosis is associated with pre-existing arterial atherosclerosis of AVF and results in significant morbidity and hospitalization for hemodialysis patients. The ankle brachial index (ABI) is a noninvasive method of assessing atherosclerosis. This study was to examine whether ABI is a significant predictor for AVF stenosis.METHODS:
This was a retrospective, longitudinal cohort study. Patients with hemodialysis between 1 January 2016 and 31 December 2022 were reviewed. ABI was assessed in January 2016. AVF stenosis was diagnosed by fistulography.RESULTS:
A total of 82 patients were included. Forty-two patients experienced AVF stenosis. The univariate logistic regression analysis showed that AVF stenosis was associated with age (OR 1.045, p = 0.033), DM status (OR 5.529, p = 0.013), 7-year averaged cholesterol level (OR 1.018, p = 0.034), 7-year averaged triglyceride level (OR 1.007, p = 0.017), and ABI (OR 0.011, p < 0.001). In multivariate logistic regression analysis, ABI was a strong predictor for AVF stenosis (OR 0.036, p = 0.023). Then, a cut-off point of ABI with optimal sensitivity and specificity for AVF stenosis was 1.01. An analysis of time to events with adjustment for other variables showed that patients with ABI < 1.01 were significantly associated with AVF stenosis (HR 3.859, p < 0.001).CONCLUSIONS:
ABI below 1.01 was associated with AVF stenosis. This finding may be useful in tailoring surveillance programs for monitoring AVF function.
Full text:
1
Database:
MEDLINE
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Language:
En
Year:
2024
Type:
Article