Vascular events in patients with head and neck cancer: A systematic review and meta-analysis.
Head Neck
; 46(7): 1557-1572, 2024 07.
Article
in En
| MEDLINE
| ID: mdl-38334324
ABSTRACT
OBJECTIVE:
To assess the incidence of vascular events in patients with head and neck cancer. REVIEWMETHODS:
Primary studies identified through April 2023. Meta-analysis was performed.RESULTS:
There were 146 studies included in the systematic review. Rates of events were collected in the overall group, those with chemoprophylaxis, and those that underwent surgery, radiation, or chemotherapy. Of 1 184 160 patients, 4.3% had a vascular event. Radiation therapy had highest risk of overall events and stroke when compared to surgery and chemotherapy. Chemotherapy had a higher risk of stroke and overall events when compared to surgery.CONCLUSIONS:
Vascular events occur in 4%-5% of patients with head and neck cancer. Our data does not support the use of routine anticoagulation. Patients undergoing radiation therapy had the highest frequency of events.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Head and Neck Neoplasms
Type of study:
Systematic_reviews
Limits:
Humans
Language:
En
Year:
2024
Type:
Article