Diagnosis and treatment of patients with suspected mucinous cystic neoplasms of the liver: a retrospective cohort study.
Langenbecks Arch Surg
; 409(1): 66, 2024 Feb 17.
Article
in En
| MEDLINE
| ID: mdl-38368313
ABSTRACT
PURPOSE:
Mucinous cystic neoplasms of the liver (MCN-L) are hepatic cysts with a low malignant potential. The recent European Association for the Study of the Liver (EASL) guidelines provide guidance on the imaging features and surgical management of MCN-L, yet are hampered by a lack of studies adhering to the revised World Health Organization (WHO) criteria. This study attempted to validate the new 2022 EASL-guidelines in a retrospective cohort study of patients who underwent surgery for suspected MCN-L.METHODS:
Patients undergoing surgery for suspected MCN-L in a single center between 2010 and 2020 were included. Imaging features were assessed according to the EASL guidelines and were compared to final pathological diagnoses, according to the WHO criteria.RESULTS:
In total, 35 patients were included. In three patients, there were no worrisome imaging features, yet final pathological diagnosis showed MCN-L. Contrarily, six patients with worrisome imaging features did not have MCN-L. Five patients were diagnosed with MCN-L on final pathology. The sensitivity of the EASL-guidelines for the diagnosis of MCN-L was 40% (95%CI 5.3-85%) and the specificity was 80% (95% CI 61-92%).CONCLUSION:
Although the new EASL-guidelines provide some guidance, they could not reliably distinguish MCN-L from other cysts in our series. Thus, preoperative diagnosis of MCN-L remains challenging and we should be careful in selecting surgical strategies based on these criteria.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Pancreatic Neoplasms
/
Neoplasms, Cystic, Mucinous, and Serous
/
Cysts
/
Liver Neoplasms
Limits:
Humans
Language:
En
Year:
2024
Type:
Article