Description of a national, multi-center registry of patients with sickle cell disease and SARS-CoV-2 infection: Data from the Pediatric COVID-19 United States Registry.
Pediatr Blood Cancer
; 71(6): e30909, 2024 Jun.
Article
in En
| MEDLINE
| ID: mdl-38469996
ABSTRACT
Children with sickle cell disease (SCD) are at risk of complications from viral infections, including SARS-CoV-2. We present the clinical characteristics and outcomes of pediatric patients with SCD from the Pediatric COVID-19 United States Registry who developed acute COVID-19 due to SARS-CoV-2 infection (n = 259) or multisystem inflammatory syndrome in children (MIS-C; n = 4). Nearly half of hospitalized children with SCD and SARS-CoV-2 infection required supplemental oxygen, though children with SCD had fewer intensive care (ICU) admissions compared to the general pediatric and immunocompromised populations. All registry patients with both SCD and MIS-C required ICU admission. Children with SCD are at risk of severe disease with SARS-CoV-2 infection, highlighting the importance of vaccination in this vulnerable population.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Registries
/
SARS-CoV-2
/
COVID-19
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Anemia, Sickle Cell
Limits:
Adolescent
/
Child
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Child, preschool
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Female
/
Humans
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Infant
/
Male
Country/Region as subject:
America do norte
Language:
En
Year:
2024
Type:
Article