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Association between direct transport to a cardiac arrest centre and survival following out-of-hospital cardiac arrest: A propensity-matched Aotearoa New Zealand study.
Dicker, Bridget; Garrett, Nick; Howie, Graham; Brett, Aroha; Scott, Tony; Stewart, Ralph; Perkins, Gavin D; Smith, Tony; Garcia, Elena; Todd, Verity F.
Affiliation
  • Dicker B; Clinical Audit and Research, Hato Hone St John New Zealand, Auckland, New Zealand.
  • Garrett N; Paramedicine Research Unit, Paramedicine Department, Auckland University of Technology, Auckland, New Zealand.
  • Howie G; Paramedicine Research Unit, Paramedicine Department, Auckland University of Technology, Auckland, New Zealand.
  • Brett A; Clinical Audit and Research, Hato Hone St John New Zealand, Auckland, New Zealand.
  • Scott T; Paramedicine Research Unit, Paramedicine Department, Auckland University of Technology, Auckland, New Zealand.
  • Stewart R; Clinical Audit and Research, Hato Hone St John New Zealand, Auckland, New Zealand.
  • Perkins GD; Cardiology Department, Northshore Hospital, Takapuna, Auckland, New Zealand.
  • Smith T; Te Toka Tumai, Auckland City Hospital, Auckland, New Zealand.
  • Garcia E; Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.
  • Todd VF; Clinical Audit and Research, Hato Hone St John New Zealand, Auckland, New Zealand.
Resusc Plus ; 18: 100625, 2024 Jun.
Article in En | MEDLINE | ID: mdl-38601710
ABSTRACT
Background and

Objectives:

Direct transport to a cardiac arrest centre following out-of-hospital cardiac arrest may be associated with higher survival. However, there is limited evidence available to support this within the New Zealand context. This study used a propensity score-matched cohort to investigate whether direct transport to a cardiac arrest centre improved survival in New Zealand.

Methods:

A retrospective cohort study was conducted using the Aotearoa New Zealand Paramedic Care Collection (ANZPaCC) database for adults treated for out-of-hospital cardiac arrest of presumed cardiac aetiology between 1 July 2018 to 30 June 2023. Propensity score-matched analysis was used to investigate survival at 30-days post-event according to the receiving hospital being a cardiac arrest centre versus a non-cardiac arrest centre.

Results:

There were 2,297 OHCA patients included. Propensity matching resulted in 554 matched pairs (n = 1108). Thirty-day survival in propensity score-matched patients transported directly to a cardiac arrest centre (56%) versus a non-cardiac arrest centre (45%) was not significantly different (adjusted Odds Ratio 0.78 95%CI 0.54, 1.13, p = 0.19). Shockable presenting rhythm, bystander CPR, and presence of STEMI were associated with a higher odds of 30 day survival (p < 0.05). Maori or Pacific Peoples ethnicity and older age were associated with lower survival (p < 0.05).

Conclusions:

This study found no statistically significant difference in outcomes for OHCA patients transferred to a cardiac arrest compared to a non-cardiac arrest centre. However, the odds ratio of 0.78, equivalent to a 22% decrease in 30-day mortality, is consistent with benefit associated with management by a cardiac arrest centre. Further research in larger cohorts with detailed information on known outcome predictors, or large randomised clinical trials are needed.
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