Outcomes in orthopedic device infections due to Streptococcus agalactiae: a retrospective cohort study.
BMC Infect Dis
; 24(1): 424, 2024 Apr 22.
Article
in En
| MEDLINE
| ID: mdl-38649829
ABSTRACT
BACKGROUND:
Group B streptococci (Streptococcus agalactiae) (GBS) is a rare cause of prosthetic joint infection (PJI) occurring in patients with comorbidities and seems to be associated with a poor outcome. Depiction of GBS PJI is scarce in the literature.METHODS:
A retrospective survey in 2 referral centers for bone joint infections was done Patients with a history of PJI associated with GBS between 2014 and 2019 were included. A descriptive analysis of treatment failure was done. Risk factors of treatment failure were assessed.RESULTS:
We included 61 patients. Among them, 41 had monomicrobial (67%) infections. The median duration of follow-up was 2 years (interquartile range 2.35) Hypertension, obesity, and diabetes mellitus were the most reported comorbidities (49%, 50%, and 36% respectively). Death was observed in 6 individuals (10%) during the initial management. The rate of success was 63% (26/41). Removal of the material was not associated with remission (p = 0.5). We did not find a specific antibiotic regimen associated with a better outcome.CONCLUSION:
The results show that S. agalactiae PJIs are associated with high rates of comorbidities and a high treatment failure rate with no optimal treatment so far.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Streptococcal Infections
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Streptococcus agalactiae
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Prosthesis-Related Infections
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Anti-Bacterial Agents
Limits:
Aged
/
Aged80
/
Female
/
Humans
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Male
/
Middle aged
Language:
En
Year:
2024
Type:
Article