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Electrochemical benzylic deuteration of p-QMs enabling the synthesis of benzylic deuterated diarylmethanes.
Yan, Yunying; Hao, Jianjun; Peng, Yulin; Yin, Mengyun; Jing, Linhai; Han, Pan.
Affiliation
  • Yan Y; Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002, China. ymy07280920@163.com.
  • Hao J; Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002, China. ymy07280920@163.com.
  • Peng Y; Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002, China. ymy07280920@163.com.
  • Yin M; Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002, China. ymy07280920@163.com.
  • Jing L; Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002, China. ymy07280920@163.com.
  • Han P; Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002, China. ymy07280920@163.com.
Org Biomol Chem ; 22(20): 4047-4051, 2024 May 22.
Article in En | MEDLINE | ID: mdl-38712523
ABSTRACT
Herein, electroreductive umpolung benzylic deuteration of p-QMs using cheap and easily accessible D2O as a deuterium source is reported. Various value-added benzylic deuterated diarylmethanes can be synthesized without the requirement of noble metal catalysts, redox reagents, and strong bases. The establishment of this protocol will provide an alternative strategy for acquiring benzylic deuterated diarylmethanes.

Full text: 1 Database: MEDLINE Language: En Year: 2024 Type: Article

Full text: 1 Database: MEDLINE Language: En Year: 2024 Type: Article