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DNA methylation-mediated 11ßHSD2 downregulation drives the increases in angiotensin-converting enzyme and angiotensin II within preeclamptic placentas.
Deng, Fengying; Lei, Jiahui; Chen, Jie; Zhao, Meng; Zhao, Chenxuan; Fu, Mengyu; Sun, Miao; Zhang, Meihua; Qiu, Junlan; Gao, Qinqin.
Affiliation
  • Deng F; Institute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
  • Lei J; Institute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
  • Chen J; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
  • Zhao M; Institute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
  • Zhao C; Department of Obstetrics and Gynecology, the Third People's Hospital of Bengbu Affiliated to Bengbu Medical College, Bengbu, Anhui, China.
  • Fu M; Institute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
  • Sun M; Department of Obstetrics and Gynecology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
  • Zhang M; Institute for Fetology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
  • Qiu J; Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, Shandong, China.
  • Gao Q; Department of Oncology and Hematology, Suzhou Hospital, Affiliated Hospital of Medical School, Nanjing University, Suzhou, Jiangsu, P.R. China.
FASEB J ; 38(11): e23714, 2024 Jun 15.
Article in En | MEDLINE | ID: mdl-38814727
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Full text: 1 Database: MEDLINE Main subject: Placenta / Pre-Eclampsia / Angiotensin II / Peptidyl-Dipeptidase A / DNA Methylation / 11-beta-Hydroxysteroid Dehydrogenase Type 2 Limits: Adult / Animals / Female / Humans / Pregnancy Language: En Year: 2024 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Placenta / Pre-Eclampsia / Angiotensin II / Peptidyl-Dipeptidase A / DNA Methylation / 11-beta-Hydroxysteroid Dehydrogenase Type 2 Limits: Adult / Animals / Female / Humans / Pregnancy Language: En Year: 2024 Type: Article