ABSTRACT
Background and
Purpose:
Skin pores (SPs) are normal and benign
skin structures that are mostly located on the
face (
nose,
cheeks, etc.) that cause many aesthetic concerns or complaints. One known effective
treatment is
botulinum toxin A (BTXA), which is also approved for the
treatment of
strabismus,
blepharospasm,
muscle spasm,
cervical dystonia, glabella wrinkles, and primary axillary
hyperhidrosis. Therefore, the aim of this study was to compare the effect of intra-dermal
injection of
botulinum toxin and
normal saline serum (NSS) in the
treatment of large facial pores.
Methods:
The study included 25 people
who referred to the
skin clinic of
Imam Khomeini
Hospital in Ahvaz from June 2021 to January 2022 for the
treatment of large facial
skin pores. Randomly, some subjects were injected with
botulinum toxin at ten points, and each point was equivalent to 2.5 units of Masport (500 units vial of Masport diluted with 10 ml of NSS). Some other people were injected with 0.05 ml of NSS by intra-dermal
injection at ten points. Finally, the data were analyzed using SPSS-Ver. 22
software.
Results:
Based on
optical coherence tomography results, it was determined that the diameter of facial pores decreased significantly (P = 0.011).
Dermoscopy showed a significant decrease in the average size of facial pores (P < 0.011), and also, the pore score decreased significantly (P = 0.021). In addition, the results showed that the size of
skin pores and facial fat on both sides of the
face did not decrease significantly from the
patients' point of view (P = 0.71).
Conclusion:
Based on the results of the present study, it can be concluded that intra-dermal
injection of
botulinum toxin is an effective and safe
method to control facial pores, which showed acceptable results after 3 months.
