Excisional biopsy of perforated gastric ulcer: mandatory or potentially harmful?
Langenbecks Arch Surg
; 409(1): 205, 2024 Jul 04.
Article
in En
| MEDLINE
| ID: mdl-38963438
ABSTRACT
PURPOSE:
This study aimed to evaluate the morbidity associated with excisional biopsy in patients with spontaneous gastric perforation.METHODS:
A retrospective, single-center, observational study was performed. All consecutive patients with spontaneous gastric perforation who underwent surgical therapy were included. Outcomes were assessed concerning the performance of excisional biopsy.RESULTS:
A total of 135 adult patients were enrolled. Of these, 110 (81.5%) patients underwent excisional biopsy, while 17 (12.6%) did not. The remaining eight (5.9%) patients who underwent gastric resection were excluded from the analysis. Patients undergoing excisional biopsy developed significantly higher rates of postoperative complications (p = 0.007) and experienced more severe complications according to the Clavien-Dindo classification, particularly type III and above (p = 0.017). However, no significant differences were observed regarding in-hospital mortality, reoperation, suture dehiscence, or length of hospital stay.CONCLUSION:
Excisional biopsy for gastric perforation has been shown to be associated with increased morbidity. Surgical closure followed by early endoscopic biopsy may be a superior approach for gastric perforation management to rule out malignancy.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Peptic Ulcer Perforation
/
Stomach Ulcer
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Year:
2024
Type:
Article