Secretion of apolipoproteins in the suckling rat. Absence of low-molecular-weight apolipoprotein B of hepatic origin.
Biochim Biophys Acta
; 837(3): 345-8, 1985 Dec 04.
Article
in En
| MEDLINE
| ID: mdl-3933567
ABSTRACT
Synthesis of apolipoprotein B in the intestine and liver in suckling rats whose duodena had been infused with [3H]lysine was estimated by measuring the radioactivity in the mesenteric lymph and blood serum. Apolipoprotein B synthesized in the suckling rat intestine was an exclusively low-molecular-weight form. In the serum d less than 1.21 g/ml fraction obtained from the lymph-diverted rats, apolipoprotein B of high molecular weight was only labeled with [3H]lysine in suckling rats, whereas both forms of apolipoprotein B were labeled in the adult rats. These results suggest developmental changes in hepatic apolipoprotein B synthesis and secretion.
Search on Google
Database:
MEDLINE
Main subject:
Apolipoproteins
/
Apolipoproteins B
/
Animal Population Groups
/
Liver
/
Animals, Suckling
Limits:
Animals
Language:
En
Year:
1985
Type:
Article