A cytoplasmically transmitted, diet-dependent difference in response to the teratogenic effects of 6-aminonicotinamide.
Science
; 160(3824): 206-7, 1968 Apr 12.
Article
in En
| MEDLINE
| ID: mdl-4230607
ABSTRACT
The frequency of congenital cleft palate produced by maternal treatment with 6-aminonicotinamide during pregnancy is lower in the C57BL/6J than in the A/J inbred mouse strain. In the C57BL/6J strain the frequency is lower when the mothers are maintained on Purina Lab Chow than when they are on Breeder Chow. A/J females do not show this effect of diet. There is a matroclinous reciprocal cross difference in frequency of induced cleft palate which persists in the back-cross when the F(1) mothers are maintained on Lab Chow but not on Breeder Chow.
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Database:
MEDLINE
Main subject:
Abnormalities, Drug-Induced
/
Pregnancy, Animal
/
Cleft Palate
/
Niacinamide
/
Extrachromosomal Inheritance
/
Maternal-Fetal Exchange
Limits:
Animals
/
Pregnancy
Language:
En
Year:
1968
Type:
Article