The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1.
Science
; 222(4629): 1248-51, 1983 Dec 16.
Article
in En
| MEDLINE
| ID: mdl-6648531
ABSTRACT
Fragments of the recently cloned human gene for the beta subunit of nerve growth factor (beta-NGF) were used as hybridization probes in analyzing two sets of rodent-human somatic cell hybrids for the presence of human beta-NGF sequences. Results from the first set of hybrids assigned the human beta-NGF gene to chromosome 1 and ruled out the presence of sequences of comparable homology on any other chromosome. With the second set of hybrids, which contained seven different, but overlapping, regions of chromosome 1, the NGF locus was mapped to band 1p22.
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Database:
MEDLINE
Main subject:
Chromosomes, Human, 1-3
/
Genes
/
Nerve Growth Factors
Limits:
Animals
/
Humans
Language:
En
Year:
1983
Type:
Article