Case report of a toxic reaction from a combination of tryptophan and phenelzine.

Thomas, J M; Rubin, E H

Thomas, J M; Rubin, E H.

Am J Psychiatry ; 141(2): 281-3, 1984 Feb.

Article in En | MEDLINE | ID: mdl-6691495

ABSTRACT

ABSTRACT

The addition of tryptophan to a monoamine oxidase inhibitor (MAOI) has been recommended for patients failing to respond to an MAOI alone. The authors report acute behavioral and neurologic toxicity immediately after tryptophan administration in a patient taking phenelzine.

Subject(s)

Bipolar Disorder/chemically induced; Movement Disorders/chemically induced; Phenelzine/administration & dosage; Tryptophan/adverse effects; Adult; Depressive Disorder/drug therapy; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Male; Phenelzine/adverse effects; Tryptophan/administration & dosage

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PubMed Links

Database: MEDLINE Main subject: Phenelzine / Tryptophan / Bipolar Disorder / Movement Disorders Limits: Adult / Humans / Male Language: En Year: 1984 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Phenelzine / Tryptophan / Bipolar Disorder / Movement Disorders Limits: Adult / Humans / Male Language: En Year: 1984 Type: Article