Piperazinylpyrazines with central serotoninmimetic activity.

Lumma, W C; Hartman, R D; Saari, W S; Engelhardt, E L; Hirschmann, R; Clineschmidt, B V; Torchiana, M L; Stone, C A

Lumma, W C; Hartman, R D; Saari, W S; Engelhardt, E L; Hirschmann, R; Clineschmidt, B V; Torchiana, M L; Stone, C A.

J Med Chem ; 21(6): 536-42, 1978 Jun.

Article in En | MEDLINE | ID: mdl-671450

Subject(s)

Pyrazines/chemical synthesis; Serotonin/physiology; Animals; Central Nervous System/drug effects; Female; In Vitro Techniques; Mice; Molecular Conformation; Muscle Contraction/drug effects; Piperazines/chemical synthesis; Piperazines/pharmacology; Pyrazines/pharmacology; Quantum Theory; Rats; Receptors, Serotonin/drug effects; Structure-Activity Relationship; Uterine Contraction/drug effects

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