Antiserum to nerve growth factor does not prevent the increase of brain stem noradrenaline after neonatal 6-hydroxydopa.
Brain Res
; 197(2): 547-53, 1980 Sep 22.
Article
in En
| MEDLINE
| ID: mdl-6773617
ABSTRACT
Antiserum to nerve growth factor (anti-NGF) given intraventricularly to newborn rats systemically injected with 6-hydroxydopa (6-OH-DOPA), did not prevent the long-term increase of brain stem noradrenaline produced by 6-OH-DOPA when given alone. Since the anti-NGF was biologically active and penetrated into the brain parenchyma, the role played by NGF in the outgrowth of central noradrenergic neurons, responsible for the elevation of brain stem noradrenaline, does not seem to be important.
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Database:
MEDLINE
Main subject:
Brain Stem
/
Dihydroxyphenylalanine
/
Norepinephrine
/
Immune Sera
/
Nerve Growth Factors
/
Nerve Regeneration
Limits:
Animals
Language:
En
Year:
1980
Type:
Article