Thermodynamic characterization of drug binding to human serum albumin by isothermal titration microcalorimetry.

Aki, H; Yamamoto, M

Aki, H; Yamamoto, M.

Affiliation

Aki H; Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Fukuoka University, Japan.

J Pharm Sci ; 83(12): 1712-6, 1994 Dec.

Article in En | MEDLINE | ID: mdl-7891299

Subject(s)

Pharmaceutical Preparations/metabolism; Serum Albumin/metabolism; Anions; Binding Sites; Calorimetry/methods; Fatty Acids/metabolism; Humans; Pharmaceutical Preparations/chemistry; Phenylbutazone/analogs & derivatives; Phenylbutazone/chemistry; Phenylbutazone/metabolism; Protein Binding; Serum Albumin/chemistry; Thermodynamics; Warfarin/chemistry; Warfarin/metabolism

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PubMed Links

Database: MEDLINE Main subject: Serum Albumin / Pharmaceutical Preparations Limits: Humans Language: En Year: 1994 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Serum Albumin / Pharmaceutical Preparations Limits: Humans Language: En Year: 1994 Type: Article