Rapidly alternating chemotherapy and hyperfractionated radiotherapy in the management of locally advanced head and neck carcinoma: four-year results of a phase I/II study.

Leyvraz, S; Pasche, P; Bauer, J; Bernasconi, S; Monnier, P

Leyvraz, S; Pasche, P; Bauer, J; Bernasconi, S; Monnier, P.

Affiliation

Leyvraz S; Department of Ear, Nose, and Throat, and Radiotherapy, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.

J Clin Oncol ; 12(9): 1876-85, 1994 Sep.

Article in En | MEDLINE | ID: mdl-8083711

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Carcinoma, Squamous Cell/drug therapy; Carcinoma, Squamous Cell/radiotherapy; Head and Neck Neoplasms/drug therapy; Head and Neck Neoplasms/radiotherapy; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Carcinoma, Squamous Cell/mortality; Cisplatin/administration & dosage; Cisplatin/adverse effects; Combined Modality Therapy; Drug Administration Schedule; Female; Fluorouracil/administration & dosage; Fluorouracil/adverse effects; Follow-Up Studies; Head and Neck Neoplasms/mortality; Humans; Leukopenia/etiology; Male; Middle Aged; Radiotherapy/adverse effects; Radiotherapy/methods; Radiotherapy Dosage; Remission Induction; Stomatitis/etiology; Survival Rate; Vindesine/administration & dosage; Vindesine/adverse effects

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Database: MEDLINE Main subject: Carcinoma, Squamous Cell / Antineoplastic Combined Chemotherapy Protocols / Head and Neck Neoplasms Type of study: Clinical_trials / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Year: 1994 Type: Article

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