The extracellular domain of the c-erbB-2 oncoprotein is released from tumor cells by proteolytic cleavage.

Pupa, S M; Ménard, S; Morelli, D; Pozzi, B; De Palo, G; Colnaghi, M I

Pupa, S M; Ménard, S; Morelli, D; Pozzi, B; De Palo, G; Colnaghi, M I.

Affiliation

Pupa SM; Division of Experimental Oncology E, Istituto Nazionale Tumori, Milan, Italy.

Oncogene ; 8(11): 2917-23, 1993 Nov.

Article in En | MEDLINE | ID: mdl-8105438

Subject(s)

ErbB Receptors/metabolism; Neoplasms/metabolism; Proto-Oncogene Proteins/metabolism; Biomarkers, Tumor/analysis; ErbB Receptors/blood; Female; Humans; Molecular Weight; Protease Inhibitors/pharmacology; Proto-Oncogene Proteins/blood; Receptor, ErbB-2; Tumor Cells, Cultured

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Database: MEDLINE Main subject: Proto-Oncogene Proteins / ErbB Receptors / Neoplasms Type of study: Prognostic_studies Limits: Female / Humans Language: En Year: 1993 Type: Article

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