Amino acid losses in ileostomy fluid on a protein-free diet.
Am J Clin Nutr
; 59(1): 70-3, 1994 Jan.
Article
in En
| MEDLINE
| ID: mdl-8279406
ABSTRACT
The contribution of losses via the gastrointestinal tract to maintenance amino acid requirements was assessed by collecting the ileostomy fluid of volunteers given a protein-free diet for 5 d. The subjects were eight adult men and women with terminal ileum ileostomies after ulcerative colitis. Four consecutive 24-h collections of both digesta and urine were made. On the last 2 d an antibiotic was given that suppressed microbial activity in the digesta and slightly reduced ileostomy outflow. Mean daily amino acid excretion in ileostomy fluid ranged from 32 mg/d for methionine to approximately 330 mg/d for aspartate and glutamate. These losses were compared with current international estimates of amino acid requirements. For most essential amino acids gastrointestinal losses accounted for 14-33% of daily maintenance requirements but for threonine the contribution was 61%.
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Database:
MEDLINE
Main subject:
Dietary Proteins
/
Ileostomy
/
Amino Acids
Limits:
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Year:
1994
Type:
Article