Identification of nonconserved amino acids in the AT1 receptor which comprise a general binding site for biphenylimidazole antagonists.

Nirula, V; Zheng, W; Krishnamurthi, K; Sandberg, K

Nirula, V; Zheng, W; Krishnamurthi, K; Sandberg, K.

Affiliation

Nirula V; Division of Nephrology and Hypertension, Department of Medicine, Georgetown University Medical Center, Washington, DC 20007, USA.

FEBS Lett ; 394(3): 361-4, 1996 Oct 07.

Article in En | MEDLINE | ID: mdl-8830675

Subject(s)

Angiotensin I/metabolism; Angiotensin Receptor Antagonists; Biphenyl Compounds/metabolism; Imidazoles/metabolism; Amino Acid Sequence; Amino Acids/metabolism; Angiotensin II/metabolism; Animals; Anura; Binding Sites/genetics; Binding, Competitive; COS Cells; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Angiotensin/genetics

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Database: MEDLINE Main subject: Biphenyl Compounds / Angiotensin I / Angiotensin Receptor Antagonists / Imidazoles Type of study: Diagnostic_studies Limits: Animals Language: En Year: 1996 Type: Article

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