IL-6 expression in neurons of transgenic mice causes reactive astrocytosis and increase in ramified microglial cells but no neuronal damage.

Fattori, E; Lazzaro, D; Musiani, P; Modesti, A; Alonzi, T; Ciliberto, G

Fattori, E; Lazzaro, D; Musiani, P; Modesti, A; Alonzi, T; Ciliberto, G.

Affiliation

Fattori E; Istituto di Ricerche di Biologia Molecolare P. Angeletti, Roma, Italy.

Eur J Neurosci ; 7(12): 2441-9, 1995 Dec 01.

Article in En | MEDLINE | ID: mdl-8845949

Subject(s)

Astrocytes/drug effects; Interleukin-6/pharmacology; Microglia/drug effects; Neurons/drug effects; Animals; Cerebellum/drug effects; Immunohistochemistry; Mice; Mice, Inbred Strains; Mice, Transgenic; RNA, Messenger/metabolism

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PubMed Links

Database: MEDLINE Main subject: Astrocytes / Interleukin-6 / Microglia / Neurons Type of study: Etiology_studies Limits: Animals Language: En Year: 1995 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Astrocytes / Interleukin-6 / Microglia / Neurons Type of study: Etiology_studies Limits: Animals Language: En Year: 1995 Type: Article