An antibody to a 17 amino acid synthetic peptide of the type I interleukin-1 receptor preferentially blocks interleukin-1 beta binding.

Clark, B D; Ikejima, T; Mancilla, J; Orencole, S F; Sirko, S P; Ishii, N; Okuda, K; Dinarello, C A

Clark, B D; Ikejima, T; Mancilla, J; Orencole, S F; Sirko, S P; Ishii, N; Okuda, K; Dinarello, C A.

Affiliation

Clark BD; Department of Medicine, Tufts University School of Medicine, Boston, MA, USA.

J Interferon Cytokine Res ; 16(12): 1079-88, 1996 Dec.

Article in En | MEDLINE | ID: mdl-8974012

Subject(s)

Antigen-Antibody Reactions; Interleukin-1/metabolism; Peptide Fragments/immunology; Protein Structure, Secondary; Receptors, Interleukin-1/immunology; Amino Acid Sequence; Animals; Binding Sites; Cell Line; Humans; Immunoglobulins/chemistry; Mice; Molecular Sequence Data; Molecular Weight; Precipitin Tests; Receptors, Interleukin-1/chemistry; Receptors, Interleukin-1/metabolism; Solubility; Tumor Cells, Cultured; Water/chemistry

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Database: MEDLINE Main subject: Peptide Fragments / Interleukin-1 / Receptors, Interleukin-1 / Protein Structure, Secondary / Antigen-Antibody Reactions Limits: Animals / Humans Language: En Year: 1996 Type: Article

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