The superantigen streptococcal pyrogenic exotoxin C (SPE-C) exhibits a novel mode of action.

Li, P L; Tiedemann, R E; Moffat, S L; Fraser, J D

Li, P L; Tiedemann, R E; Moffat, S L; Fraser, J D.

Affiliation

Li PL; Department of Molecular Medicine, University of Auckland, 92019 Auckland, New Zealand.

J Exp Med ; 186(3): 375-83, 1997 Aug 04.

Article in En | MEDLINE | ID: mdl-9236189

Subject(s)

Bacterial Proteins; Exotoxins/pharmacology; Membrane Proteins; Pyrogens/pharmacology; Streptococcus pyogenes/immunology; Superantigens/pharmacology; Cell Line; Crystallography, X-Ray; Dimerization; Exotoxins/chemistry; Exotoxins/genetics; Histocompatibility Antigens Class II/metabolism; Humans; Lymphocyte Activation/drug effects; Protein Binding/immunology; Pyrogens/chemistry; Pyrogens/genetics; Recombinant Proteins/metabolism; Structure-Activity Relationship; Superantigens/chemistry; Superantigens/genetics; Zinc/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Pyrogens / Streptococcus pyogenes / Bacterial Proteins / Superantigens / Exotoxins / Membrane Proteins Limits: Humans Language: En Year: 1997 Type: Article

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