Two alleles of the human paraoxonase gene produce different amounts of mRNA. An explanation for differences in serum concentrations of paraoxonase associated with the (Leu-Met54) polymorphism.

Leviev, I; Negro, F; James, R W

Leviev, I; Negro, F; James, R W.

Affiliation

Leviev I; Clinical Diabetes Unit, University Hospital, Geneva, Switzerland.

Arterioscler Thromb Vasc Biol ; 17(11): 2935-9, 1997 Nov.

Article in En | MEDLINE | ID: mdl-9409279

Subject(s)

Alleles; Esterases/genetics; Gene Expression Regulation; Point Mutation; RNA, Messenger/biosynthesis; Transcription, Genetic; Aryldialkylphosphatase; Codon/genetics; DNA, Complementary/genetics; Esterases/biosynthesis; Esterases/blood; Genotype; Humans; Lipoproteins, HDL/blood; Liver/metabolism; Liver Diseases/metabolism; Oxidation-Reduction; Polymerase Chain Reaction; Polymorphism, Genetic

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Database: MEDLINE Main subject: Transcription, Genetic / RNA, Messenger / Gene Expression Regulation / Point Mutation / Alleles / Esterases Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Year: 1997 Type: Article

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