Abnormalities in Alzheimer's disease fibroblasts bearing the APP670/671 mutation.

Gibson, G E; Vestling, M; Zhang, H; Szolosi, S; Alkon, D; Lannfelt, L; Gandy, S; Cowburn, R F

Gibson, G E; Vestling, M; Zhang, H; Szolosi, S; Alkon, D; Lannfelt, L; Gandy, S; Cowburn, R F.

Affiliation

Gibson GE; Cornell University Medical College at Burke Medical Research Institute, White Plains, NY 10605, USA. ggibson@med.cornell.edu

Neurobiol Aging ; 18(6): 573-80, 1997.

Article in En | MEDLINE | ID: mdl-9461055

Subject(s)

Alzheimer Disease/genetics; Alzheimer Disease/pathology; Amyloid beta-Protein Precursor/biosynthesis; Amyloid beta-Protein Precursor/genetics; Mutation/physiology; Alzheimer Disease/enzymology; Bombesin/pharmacology; Bradykinin/metabolism; Calcimycin/pharmacology; Calcium/metabolism; Fibroblasts/enzymology; Fibroblasts/metabolism; Fibroblasts/ultrastructure; Humans; Ionophores/pharmacology; Ketoglutarate Dehydrogenase Complex/metabolism; Mitochondria/metabolism; Signal Transduction/physiology

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Database: MEDLINE Main subject: Amyloid beta-Protein Precursor / Alzheimer Disease / Mutation Limits: Humans Language: En Year: 1997 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Amyloid beta-Protein Precursor / Alzheimer Disease / Mutation Limits: Humans Language: En Year: 1997 Type: Article