Antineoplastic agents. 379. Synthesis of phenstatin phosphate.

Pettit, G R; Toki, B; Herald, D L; Verdier-Pinard, P; Boyd, M R; Hamel, E; Pettit, R K

Pettit, G R; Toki, B; Herald, D L; Verdier-Pinard, P; Boyd, M R; Hamel, E; Pettit, R K.

Affiliation

Pettit GR; Cancer Research Institute and Department of Chemistry, Arizona State University, Tempe, Arizona 85287-1604, USA.

J Med Chem ; 41(10): 1688-95, 1998 May 07.

Article in En | MEDLINE | ID: mdl-9572894

Subject(s)

Antineoplastic Agents, Phytogenic/chemical synthesis; Benzophenones/chemical synthesis; Organophosphates/chemical synthesis; Prodrugs/chemical synthesis; Animals; Anti-Bacterial Agents/chemical synthesis; Anti-Bacterial Agents/pharmacology; Antineoplastic Agents, Phytogenic/pharmacology; Benzophenones/pharmacology; Cattle; Cell Division/drug effects; Colchicine/metabolism; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Leukemia P388/pathology; Macromolecular Substances; Molecular Structure; Neisseria gonorrhoeae/drug effects; Organophosphates/pharmacology; Prodrugs/pharmacology; Protein Binding/drug effects; Tubulin/drug effects; Tubulin/metabolism; Tumor Cells, Cultured

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Database: MEDLINE Main subject: Organophosphates / Benzophenones / Prodrugs / Antineoplastic Agents, Phytogenic Limits: Animals / Humans Language: En Year: 1998 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Organophosphates / Benzophenones / Prodrugs / Antineoplastic Agents, Phytogenic Limits: Animals / Humans Language: En Year: 1998 Type: Article