Complement Activation/physiology; Molecular Chaperones; Angioedema/blood; Angioedema/genetics; Animals; Antigens, CD/physiology; CD55 Antigens/physiology; Carrier Proteins/physiology; Clusterin; Collectins; Complement C1 Inactivator Proteins/deficiency; Complement C1 Inactivator Proteins/genetics; Complement Factor H/deficiency; Complement Factor H/genetics; Complement Inactivator Proteins/physiology; Complement System Proteins/physiology; Enzyme Activation; Feedback; Genes, Dominant; Glomerulonephritis, Membranoproliferative/genetics; Glomerulonephritis, Membranoproliferative/veterinary; Glycoproteins/physiology; Hemoglobinuria, Paroxysmal/blood; Hemoglobinuria, Paroxysmal/genetics; Humans; Ion Channels/physiology; Membrane Cofactor Protein; Membrane Glycoproteins/physiology; Models, Biological; Opsonin Proteins/physiology; Receptors, Complement/physiology; Swine; Swine Diseases/genetics; Vitronectin